What Causes Ankylosing Spondylitis?

 

AS Victors Club pic
AS Victors Club
Image: asvictorsclub.com

An experienced life coach, Peter Winslow owns GoldMind, LLC, in Arizona. In this capacity, he helps individuals with everything from health and healing to spiritual awareness and self-mastery. Peter Winslow also helps other individuals manage their ankylosing spondylitis (AS) as the founder of the AS Victors Club.

A form of chronic inflammation, AS affects the sacroiliac joints at the base of the lower spine. It can result in stiffness in the spine, neck, and buttocks, along with pain and loss of spine mobility due to fusion of the vertebrae. The condition is a genetic disease and cannot be prevented. Rather, people who have a high risk of AS, or those who have already been diagnosed, can work at preventing complications of the condition, such as loss of mobility.

Scientists do not know any specific cause of AS, but they have linked the condition to certain risk factors. For instance, men have a higher likelihood of developing the condition than women, and most people diagnosed with the condition are early adults or late adolescents.

Further, the condition has been connected to the HLA-B27 gene. Roughly 90 percent of people with AS have this gene. Still, the presence of this gene does not mean a person will definitely get AS. In fact, only 1 percent of people in the United States have AS, while 7 percent have the HLA-B27 gene.

In addition, scientists have linked the IL23R and ARTS1 genes to AS. These two genes are related to the body’s immune function. It’s hoped that researchers will progress toward an AS cure by studying how these two genes affect the body.

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